腹腔镜胆囊切除术术前应用长托宁的疗效观察

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腹腔镜胆囊切除术术前应用长托宁的疗效观察

李织;王天霆;张宏玲;刘文彪;李光来

【期刊名称】《中国医药指南》 【年(卷),期】2012(10)25

【摘 要】目的 了解盐酸戊乙奎醚(长托宁)作为腹腔镜胆囊切除术的麻醉前用药,对患者血压、心率、SpO2以及腺体分泌的影响.方法 选择25~50岁行腹腔镜胆囊切除手术患者100例,患者无心、肺、肝、肾、脑合并疾病,ASA分级Ⅰ~Ⅱ级,随机分为两组(I, II),每组50人,选择全身麻醉；入室后开放静脉,I组给予长托宁

0.01mg/kg缓慢静脉注射,II组给予1mL生理盐水.记录入室后(T0)、药物注射后5 min(T1)、10 min(T2)患者血压、心率、SpO2；观察药物注射后5 min、10 min、手术结束及气管导管拔除前后口腔及呼吸道分泌物清况.结果 Ⅰ组患者血压、心率、SpO2在各时点的变化差异无显着性(P>0.05),注射长托宁10 min后患者诉有轻度口干,术毕及拔管前后口腔、呼吸道无分泌物.Ⅱ组口腔分泌物多.结论 长托宁作为麻醉前用药,对血压、心率、SpO2无应激性改变；长托宁0.01mg/kg静脉注射可有效抑制口腔腺体、呼吸道分泌,保障围麻醉期口咽干燥.% Objective To understand the penehyclidine hydrochloride (Penehyclidine) as a laparoscopic cholecystectomy before the anesthesia medication, the patients the blood pressure and heart rate, and the influence of SpO2 glandular secretion. Method from 25 to 50 years old choice laparoscopic gallbladder surgery patients in 100 cases, patients unintentionally, lung, liver, kidney and brain disease merger, ASA

classificationⅠ ~ Ⅱ level, randomly divided into two groups (I, II), each


group of 50, choose general anesthesia;The home invasion opening vein, I were given"better 0.01 mg long/kg slow intravenous, II group give 1 mL saline. Record after home invasion (prearcing), drug injections of 5 min (T1), 10 min (T2) patients, the heart rate, blood pressure, SpO2; Watch drug injections of 5 min, 10 min, surgery and trachea end before and after catheter remoal of the oral cavity and the

respiratory secretions clear condition. Result Ⅰ groups of patients, the heart rate, blood pressure, in every point SpO2 the change of no significant difference (P>0.05), injection, better 10 min long after patients with mild defense dry mouth, bishop and drawing tube was before and after the mouth. No respiratory secretions. Ⅱ group more than oral secretions. Conclusion Has better as long before anesthesia medicines, the blood pressure and heart rate, SpO2 on no stress of changes; Long's 0.01 mg/kg ning intravenous can inhibit the oral glands, respiratory tract secretion, security around the anesthesia phase oropharyngeal dry. 【总页数】2页(P431-432)

【作 者】李织;王天霆;张宏玲;刘文彪;李光来

【作者单位】新疆哈密红星医院麻醉科,新疆 哈密 839000;新疆哈密红星医院麻醉科,新疆 哈密 839000;新疆哈密红星医院麻醉科,新疆 哈密 839000;新疆哈密红星医院麻醉科,新疆 哈密 839000;新疆哈密红星医院麻醉科,新疆 哈密 839000 【正文语种】中 文


【中图分类】R657.4 【相关文献】

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