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帕瑞昔布钠对妇科经腹手术全凭静脉麻醉患者的影响
秦红;柴小青;潘建辉
【期刊名称】《临床麻醉学杂志》 【年(卷),期】2012(28)7
【摘 要】目的 观察帕瑞昔布钠对妇科经腹手术行全凭静脉麻醉术后疼痛的影响.方法 全麻下行妇科经腹手术患者60例,随机均分为两组.当血流动力学指标趋于平稳后及BIS值在40～60,分别静脉注射帕瑞昔布钠40mg(5ml)(P组)和生理盐水5 ml(C组),记录给药前、给药后5、10、15、20、30、40 min的HR、MAP、BIS.并记录拔管时间、清醒时间、不良反应及拔管后45 min VAS疼痛评分.结果 P组VAS评分明显低于C组(P-＜0.05),两组给药前后BIS、HR、MAP和拔管时间、清醒时间及躁动发生率差异无统计学意义.结论 静注帕瑞昔布钠40 mg对妇科经腹手术行全凭静脉麻醉患者可显著缓解术后疼痛,对BIS值、术后拔管时间、清醒时间无明显影响.%Objective To observe the effect of parecoxib on postoperative pain during total intravenous anesthesia in patients
undergoing transabdominal gynecologic operatioa Methods Sixty patients undergoing transabdominal gynecologic operation under general anesthesia were randomly divided into two groups. Group P received intravenous parecoxib 40 mg(5 ml) and group C received normal saline 5 ml when the hemodynamics and bispectral index 40-60 were stable. HR, MAP, BIS were recorded before and 5, 10, 15, 20, 30, and 40 min after parecoxib or saline administratioa The extubation time, consciousness recovery time, side effects, and VAS score of pain at 45 min after
extubation were recorded too. Results VAS scores of pain were markedly lower in group P than that of group C (P<0. 05). There were no significant difference in hemodynamics index, the extubation time, consciousness recovery time and incidence of agitation between the two groups. Conclusion Forty mg parecoxib intravenously does not change BIS during total intravenous anesthesia and postoperative conscious recover in patients undergoing transabdominal gynecologic operation, but with a better analgesic effect. 【总页数】2页(P687-688) 【作 者】秦红;柴小青;潘建辉
【作者单位】230001 合肥市,安徽医科大学附属省立医院麻醉科;230001 合肥市,安徽医科大学附属省立医院麻醉科;230001 合肥市,安徽医科大学附属省立医院麻醉科
【正文语种】中 文 【相关文献】
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2023-04-15
